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Supports a healthy immune response & Cools inflammation

Riboflam helps cool inflammation by support­ing the whole body's healthy inflammation response with Curcumin Phytosome + maintains full-spectrum immune system functionality with Echinacea and Quercetin Phytosomes

Shop Riboflam, as seen in Men’s Health Magazine. | Bruno MD

CLINICALLY PROVEN to provide post-workout pain relief and balance inflammation response


with Exclusive Offer to Save 30%

$18.89 savings with exclusive code

30% discount first time order automatically applied at checkout

Men’s Health Magazine exclusive deal for 30% OFF Riboflam and free gift. | Bruno MD


Clinically Proven Benefits

From Pharma-grade ingredients

Clinically-proven ingredients help relieve post-exercise pain naturally

Clinically-proven ingredients help maintain a healthy heart and vascular system

Clinically-proven ingredients support cognition, mental clarity and focus

Clinically-proven ingredients help manage bad cholesterol levels by increasing bile production which traps cholesterol for elimination

Clinically-proven ingredients reduce inflammation in the gut, improve colon health and reduce gas and bloating and balance gut flora

"I exercise a lot and so I tend to get a lot of muscle and joint pain. My goal in taking Riboflam is to not have to take so many over the counter pain medicines."

Brittany A.

"I find it an essential part of my self-care routine to keep myself nice and well, so that if something does happen, if can handle it much better."

Jennifer W.

"Working out is great, but having sore muscles afterwards isn’t that fun. And this little guy here helps you reduce inflammation which means a faster recovery from your workouts."

Camila F.

"You really need to do the research of what you are putting into your body. Look for things coming from cuttable sources. And that is why I am obsessed with Bruno MD."

Megan Q.

"It’s jampacked with lots of amazing ingredients."

Michael M

"After gardening I used to feel miserable because of aching joints and soreness, not anymore, since I’ve been taking Riboflam."

Taty H.

"It really helps with muscle pain, it relieves it!"

Alexandra U.

"This product does so many good things for your body and has helped me with soreness after workouts."

Karissa H

"My family is genetically very predisposed to inflammation. I’m always really conscience of treating inflammation. I really love this supplement."

Ashley K.

Cool inflammation with Clinically Proven Ingredients

Riboflam helps men balance the body’s immune response. | Bruno MD

Don’t Boost. Balance

“Boosting” your immune system has unintended consequence

Our immune system is designed to seek and destroy pathogens, but boosting your system to respond to pathogens outside of a healthy range can throw your body into overdrive, causing a cytokine storm and potentially causing long-term or even life-threatening damage. Instead of boosting, Riboflam’s clinically-proven ingredients focus on balance. A balanced immune response does not over or underreact to invaders-instead, it activates a measured, proportional response.
Riboflam for men is highly bioavailable with new Phytosome Technology. | Bruno MD


New technology rewrites the rules of bioavailability

Our bodies have evolved to view beneficial plant-based polyphenols as useless or dangerous. For this reason, nutrients that help manage inflammation, like curcumin, are blocked by your gut before they can enter your bloodstream. No matter how much curcumin you take, the benefits are minimal without new Phytosome Technology used by Bruno MD. Phytosome uses biomimicry to wrap polyphenols in a fatty lipid, like a delivery truck. With the curcumin molecule hidden inside, the lipid passes through the gut and into your bloodstream with 3000% more bioavailability. As a result, Phytosome sets the new standard in prescription-grade natural ingredients.
Riboflam supports men’s health with Curcumin, Echinacea, Boswellia and Quercetin Phytosome as well as Astaxanthin. | Bruno MD

Coactive Health

A breakthrough formulation of ingredients: all-natural, and clinically proven

Bruno MD formulates Riboflam with three coactive elements that work powerfully together. Phytosome Complex helps regulate inflammation and balance the immune system with four unique Phytosome deliverables: Curcumin, Echinacea, Boswellia and Quercetin Phyotosome. Nucleotides Yeast Extracts help white blood cells called lymphocytes respond to pathogens. Astaxanthin is a potent anti-inflammatory and antioxidant; active in at least five different inflammation pathways to help maintain a balanced immune system and provide protection to cells from damaging free-radicals.
Riboflam uses clinically proven ingredients for men’s health. | Bruno MD

Clinically Proven Ingredients

Bruno MD uses Ingredients tested and endorsed by top research and medical institutions

All ingredients in Bruno MD products are clinically-proven and backed by hundreds of studies. One example is Curcumin; the most studied compound in the world. Bruno MD’s curcumin phytosome is independently endorsed by the prestigious Cleveland Clinic as the #1 doctor recommended curcumin formulation in the turmeric market and the formulation of choice for their leading practitioners and their patients.

Reasons To


Ingredients and Clinical Studies

Curcumin is a member of the diarylheptanoid class of natural products (curcuminoids) derived from the rhizome of Curcuma longa L., an East Indian plant, commonly called turmeric. Curcumin is the most studied compound in the world. Bruno MD’s curcumin phytosome is independently endorsed by the prestigious Cleveland Clinic as the #1 doctor recommended curcumin formulation in the turmeric market and the formulation of choice for their leading practitioners and their patients. Turmeric and has been used for thousands of years in Southeast Asia, China, and India for cooking and medicinal uses. Curcumin Phytosome is clinically proven in 35 randomized, double-blind, placebo-controlled, published clinical trials to promote a healthy inflammatory response, boost immune response, and provide relief from exercise-related pain. It works through multiple pathways on multiple targets to provide complete relief throughout the body. The extract has been standardized and contains the full bouquet of curcuminoids, not just curcumin (Curcuminoids are polyphenolic pigments and include 77% curcumin, 17% demethoxycurcumin, and 3% bisdemethoxycurcumin). It is called a “Life Guardian” because it helps control chronic inflammation and boost immune response at any age. Western scientists have rigorously tested Turmeric and its compounds for decades, including for heart disease. Results show that Turmeric has several beneficial effects on the cardiovascular system: (vii.193) Prevent or delay the development of atherosclerosis in healthy people. (vii.68) Protect the heart from inflammation and atherosclerosis promoted by chronic exposure to air pollution. (vii.194) Regulate or help lower high blood pressure. (vii.193, 195) Restores antioxidant levels and reduces free radical damage from toxic chemotherapy drugs. (vii.193) Improve age-related stiffening of blood vessels, especially combined with exercise. (vii.196) Reduce heart damage caused by chronic kidney disease (by blocking free radical damage and boosting mitochondrial function). (vii.197) Help stop the formation of dangerous blood clots, including those that cause stroke. (vii.198-199) Prevent cardiac hypertrophy due to high blood pressure, heart attack, high salt intake, or diabetes. An enlarged heart can lead to heart failure and even death. (vii.193) Protects the heart from injury caused by sepsis and chemotherapy drugs. (vii.193, 200) Turmeric’s rhizome contains potent antioxidant and anti-inflammatory compounds. Studies suggest that some of the ways turmeric compounds protect liver cells and can help prevent liver fibrosis are as follows: (vii.13) Stimulating transcription factor proteins that prompt genes to generate natural antioxidants (such as glutathione). (vii.13) Preventing activation and growth of cells in the liver that produce excess structural components. Hepatic stellate cells (HSCs) and fibroblasts are the cells mainly involved in fibrosis. (vii.13) Suppressing inflammatory transcription factors (such as NF-κB) and cytokine proteins (such as TNF-α) that can activate HSCs directly and/or indirectly. For example, TNF-α directly blocks signals from insulin, the hormone needed to metabolize blood sugar. Impaired sugar metabolism can activate HSCs. (vii.13, 31, 279) Promoting other transcription factor proteins, such as PPAR-γ, that block the activation and proliferation of HSCs. PPAR-γ also suppresses the expression of inflammatory proteins, such as the growth factor TGF-β, that promote collagen production. (vii.13, 198) Decreasing harmful triglyceride and cholesterol deposits in the liver. (vii.279) Reducing type I collagen, the primary substance in fibrotic scar tissue in the liver produced by HSCs and fibroblasts. (vii.284)
Indian Frankincense is a botanical extract harvested from the gum resin of the Boswellia Serrata tree. Boswellia Serrata Phytosome helps govern inflammatory response in the joints, bones, respiratory airways, the bowel, and brain. In addition, clinical studies have shown that a cocktail of AKBA (Acetyl-11-Keto-𝛃-Boswellic Acid) and curcumin significantly inhibit certain viral infections (viral entry) compared to the untreated control. BRUNO MD uses Boswellia Phytosome extract that is 400% more bioavailable than regular Boswellia.
The use of Echinacea is traced back to Native Americans who used it as a natural anti-inflammatory. Historically other uses include relief of mouth pain and toothache, treatment of the common cold and cough, tonsillitis relief, and treatment of septic diseases. Bruno MD cultivates our coneflower from an Italian varietal. Our plants guarantee high polysaccharides and low cross-contamination between Echinacea species. Echinacea Angustifolia Phytosome is optimized for maximum absorption. Results in clinical trials conducted using our triple-standardized Echinacea Phytosome have shown a statistically significant tendency to be more efficacious than flu vaccination alone, suggesting that E. Phytosome has the potential to act synergistically with influenza vaccination.
The Bruno MD formulation begins at the cellular base level with a Proprietary Nucleoflam Nucleotide & Nucleotides Yeast Extract Complex. These nucleotides are vital to maintaining essential cell functions and supporting a healthy immune system, digestive system, and brain function. Nucleotides also enhance the anti-inflammatory activity of Vitamin C, Vitamin D3, and Zinc. They are gluten-free, vegan, kosher, and halal. BRUNO MD combines Nucleoflam with Astaxanthin, the most potent anti-inflammatory known in Nature. Together they create a powerful shield against chronic inflammation.
Astaxanthin is the most potent anti-inflammatory known in NatureNature. In addition, natural astaxanthin has clinically demonstrated the ability to balance and strengthen the immune system while enhancing antibody production. This increase in antibodies improves our bodies’ defense against inflammation and the pathogens that can make us sick. Astaxanthin can also help reduce high blood pressure, improve heart health, prevent type II diabetes, and decrease the risk of brain damage from a stroke. Over 95% of commercial astaxanthin is synthetic. Worse, it is harvested using petrochemicals. Bruno MD Astaxanthin is naturally derived from Haematococcus Pluvialis algae, found in temperate environments around the world to produce the highest concentrations of astaxanthin with the highest bioavailability.
Quercetin is a plant-based antioxidant that has proven benefits, including anti-Inflammation properties and the promotion of Immunity. Quercetin is not an easy nutrient to get into your diet. To obtain just one daily dose of quercetin you’d need to eat about 100 kilos of broccoli. Additionally, quercetin is a polyphenol which is rejected by our bodies. Bruno MD uses Phytosome technology to bring the benefits of quercetin to every cell in your body. Research has substantiated that Quercetin Phytosome is 2000% more bioavailable than standard quercetin. Clinical studies confirm that quercetin has strong antiviral and antiinflammatory effects. A natural immunomodulator, quercetin helps block harmful viruses and bacteria and even demonstrates anti-cancer properties. The ultra bioavailability provided by the Phytosome delivery system also improves athletic performance and accelerates fitness recovery with quercetin’s proven anti-inflammatory properties. [43,44] Quercetin’s anti-inflammatory potential can be expressed on different cell types, both in animal and human models [45,46,47,48,49,50,51,52,53]. It possesses both mast cell stabilizing and gastrointestinal cytoprotective activity [54] and can also play a modulating, biphasic, and regulatory action on inflammation and immunity [53]. Additionally, quercetin has an immunosuppressive effect on dendritic cell function [55].




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